Abdominal Aortic Aneurysm Research Today is a free monthly online journal that collates and summarizes the latest research about Abdominal Aortic Aneurysm, including details on aaa (abdominal aortic aneurism), cardiac disease, treatment, symptoms, surgery.

Incidence of renal infarctions after transrenal stent placement in an animal model.

Krämer SC, Görich J, Bachmann R, Fuge D, Kuhnt B, Scharrer-Pamler R

Department of Clinical Radiology, University of Münster, Germany. kraemers@uni-muenster.de

PURPOSE: To evaluate the incidence and appearance of renal infarctions after transrenal stent placement in an animal model. METHODS: An aortic stent was placed via a femoral approach in 20 female Merino sheep. Ten animals had intentional coverage of one renal ostium with the bare struts, 1 sheep had both renal artery ostia covered, and the other 9 sheep had no stent impingement on the renal orifices. Animals were sacrificed after 3 to 12 months (mean 6) for gross pathological and histological evaluation. Infarction locations and patterns were evaluated and correlated to stent placement. RESULTS: Of the 40 renal arteries, coverage was proven at autopsy in 12 cases; the remaining 28 arteries were free of any stent overlay. Overall, 14 (35%) renal infarctions were detected; 7 were found in the 12 arteries with a transrenal stent (58.3% incidence in covered renal arteries). By comparison, the other 7 infarctions were found in the 28 unaffected arteries (25% incidence in noncovered renal arteries; p = 0.04). All infarctions appeared to be well-defined punctate lesions. CONCLUSIONS: A transrenal stent position in the abdominal aorta is related to increased renal infarctions in an animal model.

Published 9 June 2005 in J Endovasc Ther, 12(3): 312-7.
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